July 21, 2015

Health Roundup: Medical Breakhroughs

5 Exciting Ways Health-Tech Startups Are Improving Lives

1. Expanding access to healthcare knowledge
2. Building communities
3. Increasing accountability
4. Advancing research
5. Driving personalization


HIV / AIDS
Experimental Vaccine 'completely protects against the HIV virus and could have an enormous impact,' say experts

An experimental vaccine completely prevented HIV infection in half of monkeys given the jab, a new study found.
The monkeys were given the vaccine and then exposed to high doses of an aggressive virus that is the equivalent of HIV in humans.The results were so positive they spurred Johnson & Johnson to test the vaccine in people.
The international trial is underway in 400 healthy volunteers in the United States, East Africa, South Africa and Thailand.

Since it began spreading 30 years ago, AIDS has killed 40 million people worldwide.  Today, some 35 million people are infected with HIV, the virus that causes AIDS.  Despite progress in treatments, experts believe a vaccine is the best hope for eradicating the disease.

Cystic Fibrosis Breakthrough for cystic fibrosis sufferers as scientists use gene therapy to significantly improve the function of patients' lungs

A breakthrough treatment for cystic fibrosis has offered hope for thousands of patients. A landmark British study showed the gene therapy treatment significantly improved the working of patients’ lungs. The condition, which is caused by the faulty gene CFTR, leads to recurring chest infections and patients have to undergo physiotherapy up to four times a day to clear their lungs.

Scientists from Oxford University and Imperial College London have developed a treatment which repairs the faulty CFTR gene by adding a healthy gene on top, the Lancet Respiratory Medicine journal reported.  Patients inhale a virus, delivered via a nebuliser, which contains the healthy gene and ensures it reaches the cells in the lungs where it is needed.
Once inside the cells, the healthy genes help them function properly and clear mucus from the lungs.

The treatment is still in the early stages of development and has been tested on only a few patients. Professor Eric Alton, of Imperial College London, said: ‘Patients who received the gene therapy showed a significant, if modest, benefit. The results are encouraging.’ Current treatments include enzymes, proteins, or salt solutions which are inhaled through nebulisers to help thin and clear mucus from the lungs.

Pancreatic cancer.  Blood Test IDs Pancreatic Cancer in 250 of 250 Patients

“This study creates enthusiasm that early detection of pancreatic cancer, which is incurable unless removed during very early stages, might become a reality.”

Medical advance.  Blood Test The simple blood test that reveals ANY virus you've ever had - and could help doctors diagnose patients with 'mystery illnesses'

A simple test could reveal any viruses a person has ever had - allowing for better diagnosis of disease. The new tool can detect hundreds of viruses at a time from just a single drop of blood.  The test, called VirScan, makes it possible to test for all current and past infections, rather than testing for specific viruses at a time. It also only costs $25 (£16), a fraction of the cost of existing tools, and uses smaller samples of blood, US researchers say. VirScan works by screening the blood for antibodies against any of the 206 species of viruses known to infect humans.

Testing for a wider range of viruses can uncover unexpected factors affecting individual patients' health – and can help doctors make better diagnoses. It also allows researchers to see similarities and differences in large populations. This could be helpful when studying conditions such as Chronic Fatigue Syndrome, which is suspected to be caused by viruses, although the link has not been established

Tuberculosis Could a common heartburn drug cure TUBERCULOSIS? Prevacid offers 'excellent' hope of new treatment, say scientists

TB continues to be a global pandemic, second only to Aids as the greatest single-agent killer in the world.
In 2013 alone, the TB bug mychobacterium tuberculosis was responsible for 1.5 million deaths and almost nine million new infections. Resistance to TB drugs is widespread, creating an urgent need for new medicines.
Swiss scientists screened a number of existing drugs in hope of finding new treatments to counter TB, which caused 1.5 million deaths in 2013. Lansoprazole, marketed as Prevacid, is an antacid used to treat heartburn. They say the class of drug offers 'an excellent opportunity to treat TB'

Lansoprazole belongs to a class of drugs known as 'proton-pump inhibitors' that keep the stomach from pumping too much acid, thus preventing heartburn and ulcers.  Professor Stewart Cole, who led the research, said: 'Proton-pump inhibitors are both safe and widely sold around the world.
Posted by Jill Fallon at 1:31 PM | Permalink
Categories: Health

July 12, 2015

Health Roundup: Cancer Edition: immuno-oncology, skin, breast and lung cancers

The Economist Doctors are trying—with some success—to recruit the immune system to help with the war on cancer .  There are four ways of dealing with cancer: surgery, radiation, chemotherapy and targeted therapies.  Now scientists are adding a fifth: "immuno-oncology" like Bristol Myers' Opdivo or the arthritis vaccine currently in trials.

Like targeted treatments, these new approaches often use antibodies—proteins that match up to other proteins with great specificity. Unlike the targeted therapies, though, the new treatments do not directly attack cancerous cells, but instead unleash the immune system on them.


Skin cancer
Skin cancer jab 'can give TEN more years of life':

Trials have shown that Opdivo boosts average survival rates by 56 per cent.  Doctors said it marked a ‘major milestone’ in the fight against skin cancer. Trials have shown that Opdivo – a brand name for the drug nivolumab – boosts average survival rates by 56 per cent and some patients who had been given months to live have since returned to work.

It is one of a new type of drugs in so-called immunotherapy, which work by teaching the body’s immune system to attack cancerous cells. Experts describe them as a ‘paradigm shift’ in the war against cancer and they are particularly effective against some of the deadliest tumors.

The FDA granted accelerated approval for Skin Cancer Drug Opdivo in Dec 2014

The drug developed by Bristol-Myers Squibb costs about  $12,500 per month, or  $150,000 annually.  Opdivo, is a PD-1 inhibitor. PD-1 helps cancer cells masks their presence in the body, which allows them to grow and metastasize before the immune system can detect and attack them.

Lung cancer  The FDA expanded the approved use of Opdivo (nivolumab) to treat patients with advanced (metastatic) squamous non-small cell lung cancer (NSCLC) with progression on or after platinum-based chemotherapy.
Lung cancer is the leading cause of cancer death in the United States, with an estimated 224,210 new diagnoses and 159,260 deaths in 2014.

Arthritis. Jab that targets agony of arthritis using patient's own cells: Could help hundreds of thousands by preventing painful swelling

Rheumatoid arthritis is caused by immune system mistakenly attack joints. The Vaccine 're-educates' the immune system not to attack healthy tissue and the jab is also said to be kinder to the body than existing drugs.  While longer trials of the drug are needed,  experts are so far excited by results.

Breast cancer Fresh doubts over breast cancer tests: Harvard finds routine screening fails to cut deaths

A Harvard study of 16 million women has cast doubt on the benefits of routinely offering breast cancer screening.
The data suggests that routine screening is leading to significant numbers of ‘false positives’ – in which women are wrongly told they might have breast cancer when, in fact, they do not. Other women might undergo grueling chemotherapy to treat small, slow-growing tumors which might never have troubled them if they lived on in ignorance.

Breast cancer Hormone in The Pill 'shrinks tumors in half of cases', say scientists

Progesterone could help treat half of all breast cancer patients, say experts.  The hormone, found in many contraceptive pills, is involved in signals between cell molecules that can hold back tumor growth
Experts reveal progesterone receptor 'talks to' other receptors sensitive to estrogen, which fuels breast cancer in many cases Has the effect of applying a brake on the estrogen receptor's ability to stimulate tumors, research reveals.

Breast Cancer: Eradicating a single protein in the blood could stop breast cancer in its tracks, scientists say

Scientists have identified a key molecule, a single protein which triggers the growth of blood vessels in tumors that have spread to the brain - a common secondary site for breast cancer to spread. By withholding the protein, called DOCK4, a particular part of the blood vessel did not form as quickly, meaning tumors grew at a slower rate, scientists found.
Dr Georgia Mavria, from the University of Leeds, said the discovery could help develop new drugs and identify people at risk of their breast cancer spreading.


Melanoma. Deadly Melanoma May Not Show Up as a Mole

But a new study finds that the sometimes-deadly skin cancer melanoma usually arises in normal skin, where there is no dark spot or sign of cancer until the melanoma suddenly shows up.  Moreover, melanomas that arise in non-mole areas of the skin tend to be more aggressive and deadly than those that do arise from moles, the study found.
----
People whose melanomas did not arise from moles (called de novo melanomas) tended to do worse than people with mole-associated melanoma, the researchers said in their findings, presented June 1 at the annual American Society of Clinical Oncology meeting…..In general, between 20 and 30 percent of melanomas are mole-associated, but themajority of melanoma cases are de novo cases — they arise in skin that looks normal until the melanoma forms.

How being obese could help you FIGHT cancer 

Overweight patients survive 3 months longer than thinner peers surprising study reveals. While the study does not indicate that being overweight is in any way protective for patients undergoing cancer treatment, Dr Zafar said…. the results suggest that there could be an aspect of biology that could put thinner patients at a higher risk for poor outcomes.. Dr Zafar continued,  'There may be a relationship between having a lower BMI and how much treatment patients can tolerate.'I would hypothesise that the lowest weight patients in our analysis received or tolerated less treatment, or received adequate treatment at first, but became too sick to receive additional therapy.
Posted by Jill Fallon at 7:40 PM | Permalink
Categories: Health

July 11, 2015

Health Roundup: Autism, depression, diabetes, dementia, hospital stays and delirium

Mental Illness: Schizophrenia. Have scientists discovered what causes schizophrenia? Condition may occur because 'gene mutations disrupt chemical balance of the brain'

Autism. People with autism have 'supercharged' brains: Those with the condition are 'over-sensitive to the world - and not impaired'

Scientists found rats reared in a predictable environment were less likely to exhibit some of the symptoms of autism
Findings consistent with the theory that autism is the consequence of supercharged brains that make the world an intensely painful place  Experts hope their findings will help develop new therapies to treat autism.

Can autism be diagnosed by a child's sense of SMELL? Children with the disorder continue to sniff a bad odor for longer than those without

Children without autism have a sniff response in which they try and limit the flow of air through their nose when they smell something bad But children with the disorder continue to smell the odor . New sniff test was accurate in diagnosing autism in 81% of children.  Increasingly abnormal sniff response was associated with more severe symptoms of autism

Depression Depression SHRINKS key part of the brain responsible for creating new memories, scans reveal

The large study of nearly 9000 people compared brain volumes in those with/without depression.
--
Those who suffer chronic depression have a significantly smaller hippocampus than healthy individuals, researchers discovered.  The mental illness tends to shrink this area of the brain which is  associated with creating new memories, storing memories and connecting them to our emotions.  The study highlights the need to treat depression in teenagers to stop further bouts.


Diabetes. Is type 2 diabetes caused by BACTERIA in the gut? Toxins trigger insulin resistance and high blood sugar levels, study finds

Bacteria responsible for common skin infections, food poisoning and MRSA could also trigger one of the most prevalent diseases of our time - type 2 diabetes.  Type 2 diabetes comprises 90 per cent of all people with diabetes. Scientists at the University of Iowa  discovered exposure to Staphylococcus aureus bacteria causes  insulin resistance, glucose intolerance, and systemic inflammation - hallmark symptoms of the disease in rabbits.  Professor Patrick Schlievert, who led the study, said: 'We basically reproduced type 2 diabetes in rabbits simply through chronic exposure to the staph superantigen."

Obesity,  a known risk factor for developing type 2 diabetes, alters a person's microbiome - the ecosystem of bacteria that colonize a person's gut, and affect their health.  Professor Schlievert said: 'What we are finding is that as people gain weight, they are increasingly likely to be colonized by staph bacteria - to have large numbers of these bacteria living on the surface of their skin.  'People who are colonized by staph bacteria are being chronically exposed to the superantigens the bacteria are producing.'  Professor Schlievert's past research has shown that superantigens - the toxins produced by all strains of staph bacteria - disrupt the immune system.

Diabetes and Dementia Could diabetes trigger DEMENTIA? People with type 2 suffer 'memory loss and declining decision-making skills'

People with type 2 diabetes lose brain power as their ability to regulate blood flow drops, research suggests.
A study by experts at Harvard Medical School suggests that the impact can be seen in memory and cognition tests - with the decrease in thinking skills dropping over just two years.  They found a significant decrease in cognitive power, which impacted their ability to cook and bathe themselves.

The study size was small. The US researchers tracked 40 people over two years.  Of those, 19 had type two diabetes and 21 did not have diabetes.Study leader Dr Vera Novak, whose work was published in the journal Neurology, said: ‘Normal blood flow regulation allows the brain to redistribute blood to areas of the brain that have increased activity while performing certain tasks.

Dementia.  Blocking a protein that builds up in the blood 'helps combat memory loss'

A protein that accumulates in the blood as we age may provide the basis for new treatments to reverse dementia, research has shown. The molecule, dubbed B2M, is found in higher concentrations in the blood and cerebral spinal fluid of aging humans, scientists said.  And in mice, inhibiting B2M improved learning and memory in laboratory experiments.  And mice genetically bred not to have B2M did not develop memory decline
'We are very excited about the findings because it indicates that there are two ways to potentially reverse age-related cognitive impairments,' study co-author Dr Saul Villeda of the University of California, San Francisco.

Delirium Delirium: A Surprising Side Effect of Hospital Stays

Often misdiagnosed as dementia, delirium can cause hallucinations and delusions…….Turpin’s experience illustrates the consequences of delirium, a sudden disruption of consciousness and cognition marked by vivid hallucinations, delusions and an inability to focus that affects 7 million hospitalized Americans annually. The disorder can occur at any age — it has been seen in preschoolers — but disproportionately affects people older than 65 and is often misdiagnosed as dementia.

While delirium and dementia can coexist, they are distinctly different illnesses. Dementia develops gradually and worsens progressively, while delirium occurs suddenly and typically fluctuates during the course of a day. Some patients with delirium are agitated and combative, while others are lethargic and inattentive.
-----
Patients treated in intensive care units who are heavily sedated and on ventilators are particularly likely to become delirious; some studies place the rate as high as 85 percent. But the condition is common among patients recovering from surgery and in those with something as easily treated as a urinary tract infection. Regardless of its cause, delirium can persist for months after discharge.
--
A recent meta-analysis led by Harvard researchers found that a variety of non-drug interventions — which included making sure patients’ sleep-wake cycles were preserved, that they had their eyeglasses and hearing aids and that were not dehydrated — reduced delirium by 53 percent. These simple fixes had an added benefit: They cut the rate of falls among hospitalized patients by 62 percent.
Posted by Jill Fallon at 10:56 AM | Permalink
Categories: Health

My broken arm

The reason why I haven't been posting for the past month is simple -  I broke my right arm in a freak accident.  Among the many things you can not do easily with one arm in a sling is typing and blogging.  But my doctor says that my recovery is "ahead of schedule."  It's amazing what a lot of sleep, rest and Advil can do. 

Since I've been doing exercises to increase my range of motion, I've started typing again.  And now blogging.

Posted by Jill Fallon at 10:52 AM | Permalink
About Business of Life™
About the Author
Contact Us
Companion Weblogs
Legacy Matters™
Estate Legacy Vaults (ELV)

Pajamas Media BlogRoll Member
Subscribe






Google Reader or Homepage
del.icio.us Business of Life
Add to My Yahoo!
Subscribe in NewsGator Online

myFeedster
Add to My AOL
Subscribe in Furl
Subscribe in Rojo
Subscribe with Bloglines

Categories
Aging with Grace and Grit
Art
BlogHer
Books
Brave New World
Career
Caregiving
Checklists
Civilization - Can We Keep It?
Culture and Society
Death and Dying
Disasters, natural and manmade
Divorced or Widowed
Economy
Education
Environment
Family
Financial Planning, Wealth
Giving and Philanthropy
Government
Happiness
Health
Identity and Security
Idiocies
Inheritance
Integrating Mind, Body, Spirit
Just for Fun
Legal Matters
Love, Marriage and Weddings
Meaning, Passion and Purpose
Movies, Videos
New words for emotions and new words
Organizing and Practical Tips
Parenting
Personal Development
Preparedness/What Every Adult Should Have
Retirement
Rules of Life/Lessons Learned
Science/ wonders
Signs of the Times
Spirituality and Religion
The Sexes
Transitions
Virtue
Wise Words and Quotations
Articles
Why Legacy Matters
Women of a Certain Age
Search
Google
www.estatevaults.com
Latest Entries
Health Roundup: Medical Breakhroughs
Health Roundup: Cancer Edition: immuno-oncology, skin, breast and lung cancers
Health Roundup: Autism, depression, diabetes, dementia, hospital stays and delirium
My broken arm
Miscellany
Practical tips
Your public servants at work
Government employees
Health Roundup: Cancer edition
Health roundup: oral edition
When air traffic controllers are hired on the basis of their skin color, not their competence
Health Roundup: Asthma, malaria vaccine, Alzheimer's, anorexia and leaky gut
Miscellany
"Honor sacrifice by tending to the tree of liberty"
The 0.3% Consensus
Cancer charity fraud
Untranslatable Words
Amazing story
"Health, safety and security…have replaced faith, hope and charity as virtues"
Miscellany
How to Build a Human
Smart kid
"First, there is indifference. Second, there is emotional anger. Third, there is force".
Miscellany
Iran is running out of water
Making chocolate even better
"A lively exchange of one idea"
Practical tips of the week
"For the sexual revolutionaries, it’s the state against the church"
We are not protected against the 'electromagnetic-pulse barbarians of the 21st century'
Religious roots of common words
Iraqi Catholic Nun Denied Entry into U.S. She wants to speak of plight of Christians persecuted by ISIS
A CARD that unlocks your phone
Palate Cleanser
David Simon, creator of The Wire, blames O'Malley for Baltimore's Anguish
"[T]he Sexual Revolution..is many times more terrible than the supposed patriarchy it supplanted"
Baltimore "Keep voting for the same thing, keep getting the same thing."
Treating patients at home
"We spy on each other"
Too much technology is making it hard for children to read facial expressions
Miscellany
Adolf Hitler,“Who, after all, speaks today of the annihilation of the Armenians?”
Why I support the death penalty for convicted terrorists
Health roundup: Depression, Alzheimer's, MS, Cancer, Genetic Treatments and Vaccinations
Some practical tips you can use
Celebrating Earth Day with Michael Crichton
More on the Wisconsin John Doe investigations and Trust in Government
The 20th century Genocides Even Our Government Is Afraid to Recognize
This is a safe time for kids to play outside and unsupervised
Killing Birds
Quotes of Note

If you deliberately plan on being less than you are capable of being, then I warn you that you'll be unhappy for the rest of your life. -Abraham Maslow

Growth in wisdom may be exactly measured by decrease in bitterness. -Friedrich Nietzsche

How wonderful is it that nobody need wait a single moment before starting to improve the world? -Anne Frank

Calendar
July 2015
Sun Mon Tue Wed Thu Fri Sat
      1 2 3 4
5 6 7 8 9 10 11
12 13 14 15 16 17 18
19 20 21 22 23 24 25
26 27 28 29 30 31  
Links
Marriage
Marriage Movement a grass-roots movement to strengthen marriage, it’s civil and intellectual with good links
Parenting
Independent Means Joline Godfrey on raising financially fit and good kids
Spiritual Parenting Mimi Doe on raising kind, honorable children connected to their spirit
American Baby Preconception, Adoption, Pregnancy, Baby, Toddlers and Kids and lots of ads
Blogging Baby Covering what they think is interesting
Daddy Types for new dads
Dad Talk news for serious parents
Dot Moms all sorts
Dooce rhymes with juice
Testosterhome stay at home writer with four young sons
raising grandchildren when parents can’t
Halley’s Comment Halley Suitt is a writer, editor, mom and all-purpose provocateur from Boston, as well as the blog czarina at Worthwhile
Divorce
emergency divorce blog for women
Divorce Transitions Information and support community
Widowed
Widows Resource Help for widows as they solve financial and legal problems despite their grief
Career
Worthwhile Work with purpose, passion and profit
Occupational Adventure - On having a career that lights your fire
Wealth
Womens’ Wall Street Because it’s your money: Tools, columns and ask Jane Dough Motley Fool To educate, amuse and enrich
Transitions
William Bridges Transitions are the inner work we do to come to terms with change. Personal and corporate transitions, he understands them better than anyone and how to make the most of change
The Paper Room my friend Sydney Rice’s Choices for career and life enrichment
Home and Moving
This Old House - Homeowner know-how
Monthly Home Maintenance Checklists
Moving Lady - Transform relocation into a creative life transition
Retirement
What retirement? boomer approaches retirement
Health
ACOR Association of Cancer Online Resources. Lots of links, many online support groups
After Abortion Life after abortion: news, opinion, personal experience, resources
Health Facts and Fears From the American Council on Science and Health
Your Disease Risk From Harvard, rate your personal risk for cancer, diabetes, heart disease, stroke and osteoporosis and get personalized tips for prevention
Your Health Record Maintaining a Treasure Chest
Nutrition Navigator Rating nutrition sites
Medline Plus Your first stop in any Internet health search. NIH’s National Library of Medicine. 650 topics
HealthWeb Linking you to the Best in Health Information
Dr. Green An online pediatrician, with a daily dose, daily chats and over 5000 pages of info
Living with Illness
Tumor diary living with brain cancer
I will survive living with breast cancer
Cancer Blog

Aging and Caregiving
As Time Goes By - What it’s really like to get older
Aging Solutions Aging parents and elder care, good checklists, resources, elder care 101, independent living and more
Benefits Checkup Over 55? From the National Council on Aging, a free service to find what benefits you may be entitled to
What’s It All About
Integral Naked Stimulating, provocative and spiritual
Pause Living without a Net
Lifestylism Creating the life you want
You already know this stuff
Zaadz Do what you do best…better
Experience Designer how do you learn the things you value most
Foundation for a Better Life good news
Beliefnet Everyone believes in something
Miscellaneous
Surprise Gifts The best gift ideas on the Web. Great categories
Cool Tools Kevin Kelly’s on all sorts of tools that work
Date Archives
July 2015
June 2015
May 2015
April 2015
March 2015
February 2015
January 2015
December 2014
November 2014
October 2014
September 2014
August 2014
July 2014
June 2014
May 2014
April 2014
March 2014
February 2014
January 2014
December 2013
November 2013
October 2013
September 2013
August 2013
July 2013
June 2013
May 2013
April 2013
March 2013
February 2013
January 2013
December 2012
November 2012
October 2012
September 2012
August 2012
July 2012
June 2012
May 2012
April 2012
March 2012
February 2012
January 2012
December 2011
November 2011
October 2011
September 2011
August 2011
July 2011
June 2011
May 2011
April 2011
March 2011
February 2011
January 2011
December 2010
November 2010
October 2010
September 2010
August 2010
July 2010
June 2010
May 2010
April 2010
March 2010
February 2010
January 2010
December 2009
November 2009
October 2009
September 2009
August 2009
July 2009
June 2009
May 2009
April 2009
March 2009
February 2009
January 2009
December 2008
November 2008
October 2008
September 2008
August 2008
July 2008
June 2008
May 2008
April 2008
March 2008
February 2008
January 2008
December 2007
November 2007
October 2007
September 2007
August 2007
July 2007
June 2007
May 2007
April 2007
March 2007
February 2007
January 2007
December 2006
November 2006
October 2006
September 2006
August 2006
July 2006
June 2006
May 2006
April 2006
March 2006
February 2006
January 2006
December 2005
November 2005
October 2005
September 2005
August 2005
July 2005
June 2005
May 2005
April 2005
March 2005
February 2005
January 2005
December 2004
November 2004
October 2004
September 2004
August 2004
July 2004
June 2004
May 2004
April 2004
February 2004
January 2004
BlogHerRoll
Advertisements
Recommended Reading
Wealth
Personal Development
Career
Transitions
Losing Loved Ones
Organizing
Powered by
Movable Type 3.33